In the short-term, inflammation is a good thing: it’s the body’s first line of defense against bacteria, viruses, and toxins that can harm our health. But when inflammation lingers, it can lead to a whole bunch of not-fun symptoms, including fatigue, fever, poor digestion, and achy joints. Chronic inflammation has also been linked to the development of serious health issues later in life. Getting inflammation under control can be tricky, but research has shown that a combination of healthy diet choices and anti-inflammatory supplements can help. If you’re experiencing symptoms of inflammation, these are the best supplements to reduce inflammation, according to science.